The NLGN2 Polyclonal Antibody (CAB14289) is specifically designed for researchers studying NLGN2, a cell adhesion molecule that plays a crucial role in synapse formation and function in the brain. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the NLGN2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent tool for studies in neuroscience and neurodevelopmental disorders.NLGN2, a member of the neuroligin family, is essential for the proper communication between neurons and is implicated in various neurological conditions such as autism spectrum disorders, schizophrenia, and intellectual disabilities.
Research into the function and regulation of NLGN2 is vital for advancing our understanding of synaptic transmission and potentially identifying new therapeutic targets for neurodevelopmental disorders.Overall, the NLGN2 Polyclonal Antibody (CAB14289) is a valuable tool for scientists investigating the role of NLGN2 in synaptic plasticity, neuronal development, and neurological diseases, ultimately contributing to the advancement of neuroscience research.
Product Name:
NLGN2 Rabbit Polyclonal Antibody
SKU:
CAB14289
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 15-180 of human NLGN2 (NP_065846.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, presynaptic cell membrane, synapse.
Calculated MW:
91kDa
Observed MW:
91kDa
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
Purification Method:
Affinity purification
Gene ID:
57555
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using NLGN2 Rabbit pAb (CAB14289) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
