The NLGN1 Polyclonal Antibody (CAB16105) is a powerful tool for research involving NLGN1, a neuronal cell adhesion molecule crucial for synaptic function and neuronal development. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples, making it a reliable choice for experiments such as Western blotting.NLGN1 plays a key role in synaptic transmission and plasticity, making it a valuable target for studies in neuroscience and neurodevelopmental disorders. By binding specifically to NLGN1, this antibody allows for the detection and analysis of NLGN1 expression in various cell types, providing valuable insights into the mechanisms underlying neuronal communication and signaling pathways.
Research on NLGN1 has implications for understanding neurological disorders such as autism spectrum disorders, schizophrenia, and intellectual disabilities, as mutations in NLGN1 have been associated with these conditions. By studying NLGN1 with the help of this antibody, researchers can uncover new therapeutic strategies and potential targets for drug development in the field of neuroscience.
Product Name:
NLGN1 Rabbit Polyclonal Antibody
SKU:
CAB16105
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NLGN1 (NP_055747.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, postsynaptic density, synapse
Calculated MW:
96kDa
Observed MW:
105kDa
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
Purification Method:
Affinity purification
Gene ID:
22871
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using NLGN1 Rabbit pAb (CAB16105) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 6min.
