The NKX2-3 Polyclonal Antibody (PAC060288) is a valuable tool for researchers studying the NKX2-3 protein, which is a key transcription factor involved in the development and function of the gastrointestinal system. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blotting.NKX2-3 plays a crucial role in regulating the expression of genes involved in intestinal development and maintenance. Dysregulation of NKX2-3 has been implicated in various gastrointestinal disorders, including inflammatory bowel disease and colorectal cancer.
By targeting the NKX2-3 protein, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially identify novel therapeutic targets.Overall, the NKX2-3 Polyclonal Antibody is a reliable tool for investigating the function of NKX2-3 in gastrointestinal health and disease. Its specificity and sensitivity make it an ideal choice for researchers interested in unraveling the complexities of gastrointestinal biology.
Antibody Name:
NKX2-3 Antibody (PACO60288)
Antibody SKU:
PACO60288
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Homeobox protein Nkx-2.3 protein (52-148AA)
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: NKX2-3 antibody at 3.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa.
Background:
Transcription factor.
Synonyms:
Homeobox protein Nkx-2.3 (Homeobox protein NK-2 homolog C), NKX2-3, NKX23 NKX2C
UniProt Protein Function:
NKX2-3: Transcription factor. Belongs to the NK-2 homeobox family.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 10q24.2
UniProt Protein Details:
NCBI Summary:
This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.[provided by RefSeq, Mar 2010]
