NKX2-1 Rabbit Polyclonal Antibody (CAB3097)
- SKU:
- CAB3097
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NKX2-1 Rabbit Polyclonal Antibody |
SKU: | CAB3097 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human NKX2-1 (NP_003308.1). |
Sequence: | LEES YKKV GMEG GGLG APLA AYRQ GQAA PPTA AMQQ HAVG HHGA VTAA YHMT AAGV PQLS HSAV GGYC NGNL GNMS ELPP YQDT MRNS ASG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | BCH; BHC; NK-2; TEBP; TTF1; NKX2A; NMTC1; T/EBP; TITF1; TTF-1; NKX2.1; NKX2-1 |
Positive Sample: | NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Purification Method: | Affinity purification |
Gene ID: | 7080 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |