NKp44 Monoclonal Antibody [PAT1G6AT] (CPAB0619)
- SKU:
- CPAB0619
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT1G6AT
- Applications:
- WB
- ELISA
Description
NKp44 Monoclonal Antibody [PAT1G6AT] (CPAB0619)
The NKP44 Polyclonal Antibody (CPAB0619) is a valuable tool for researchers studying natural killer cell biology and immune response regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for a variety of research applications.NKP44, a natural cytotoxicity receptor expressed on NK cells, plays a crucial role in the regulation of immune responses and the recognition of target cells. By targeting the NKP44 protein, this antibody allows for the detection and analysis of NKP44 expression in different cell types, providing insights into the function and activity of NK cells in various contexts.
In the field of immunology and cancer research, understanding the role of NKP44 in immune surveillance and tumor cell recognition has significant implications for the development of novel therapies and immunotherapies. The NKP44 Polyclonal Antibody (CPAB0619) offers researchers a reliable tool for investigating the mechanisms underlying NK cell-mediated cytotoxicity and immune regulation.
Product Name: | NKp44 Antibody |
Product Sku: | CPAB0619 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human NKp44 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NKp44 protein 19-13 amino acids purified from Ecoli. |
Clone: | PAT1G6AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | NKp44 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | NCR2 (NKp44) belongs to the natural cytotoxicity receptor (NCR) family which is expressed on activated human NK cells. NKp44 exhibits a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), possibly involved in the association with KARAP/DAP12 molecules. The gene coding for NKp44 maps on human chromosome 6p21.1. |
Synonyms: | Natural cytotoxicity triggering receptor 2, Natural killer cell p44-related protein, NK cell-activating receptor, Lymphocyte antigen 95 homolog, NK-p44, NKp44, CD336, NCR2, LY95, dJ149M18.1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |