The NKIRAS2 Polyclonal Antibody (PACO10862) is a valuable tool for researchers studying NKIRAS2, a protein involved in immune regulation and cell signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the NKIRAS2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it well-suited for investigations in immunology and cancer research.NKIRAS2, also known as NF-kappa-B inhibitor-interacting Ras-like protein 2, plays a crucial role in modulating immune responses and inflammatory processes.
Its involvement in signaling cascades suggests its potential as a therapeutic target for diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the functions and interactions of NKIRAS2 is key to developing targeted treatments that can manipulate immune responses for therapeutic benefit.In summary, the NKIRAS2 Polyclonal Antibody is a valuable resource for researchers aiming to elucidate the role of NKIRAS2 in immune regulation and disease pathology. Its specificity and reliability make it an essential tool for advancing our understanding of immune responses and developing novel therapeutic strategies.
NKIRAS2: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric, Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 17q21.2
