The NKIRAS1 Polyclonal Antibody (CAB14878) is specifically designed for research involving NKIRAS1, a crucial regulator of immune response and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the NKIRAS1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal tool for studies in immunology and inflammatory conditions.NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, plays a pivotal role in modulating NF-kappa-B signaling pathway, leading to the regulation of inflammatory responses.
The significance of NKIRAS1 in immune regulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of NKIRAS1 is essential for developing therapies that target immune response modulation in these disease contexts.
Product Name:
NKIRAS1 Rabbit Polyclonal Antibody
SKU:
CAB14878
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 118-192 of human NKIRAS1 (NP_065078.1).
Predicted to enable GTPase activating protein binding activity. Predicted to be involved in I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within several processes, including Ral protein signal transduction; lung alveolus development; and surfactant homeostasis. Located in cytosol and endoplasmic reticulum.
Purification Method:
Affinity purification
Gene ID:
28512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NKIRAS1 Rabbit pAb (CAB14878) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.