The NKG2D Ligand 2 Polyclonal Antibody (CAB8264) is a vital tool for researchers studying the NKG2D ligand 2 protein, a key molecule involved in immune recognition and response. This antibody is produced using rabbit immunization and is specifically designed for use with human samples. Validated for Western blot applications, it effectively binds to the NKG2D ligand 2 protein, allowing for precise detection and analysis across different cell types.NKG2D ligand 2, also known as a crucial player in immune surveillance, plays a significant role in the body's defense against infected or malignant cells.
By understanding the function and expression of this protein, researchers can gain insights into the immune response to diseases like cancer, viral infections, and autoimmune disorders. The NKG2D Ligand 2 Polyclonal Antibody is essential for studies in immunology and oncology, providing valuable information for the development of innovative therapeutic approaches.
Product Name:
ULBP2 Rabbit Polyclonal Antibody
SKU:
CAB8264
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ULBP2 (NP_079493.1).
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
80328
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of THP-1, using ULBP2 antibody (CAB8264) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
