ULBP1 Rabbit Polyclonal Antibody (CAB10483)
- SKU:
- CAB10483
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | ULBP1 Rabbit Polyclonal Antibody |
SKU: | CAB10483 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP1 (NP_079494.1). |
Sequence: | GWVD THCL CYDF IITP KSRP EPQW CEVQ GLVD ERPF LHYD CVNH KAKA FASL GKKV NVTK TWEE QTET LRDV VDFL KGQL LDIQ VENL IPIE PLTL QARM SCEH EAHG HGRG SWQF LFNG QKFL LFDS NNRK WTAL HPGA KKMT EKWE KNRD VTMF FQKI SLGD CKMW LEEF LMYW EQML DPTK PPSL APG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:100 - 1:500 |
Synonyms: | N2DL-1; RAET1I; NKG2DL1; ULBP1 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum, GPI-anchor, Lipid-anchor. |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 80329 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |