The NKD1 Rabbit Polyclonal Antibody (CAB17799) is an essential tool for researchers studying NKD1, a protein involved in Wnt signaling pathway regulation and cell development. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for a variety of research applications, including Western blotting and immunohistochemistry.NKD1, also known as Naked cuticle homolog 1, is a key player in embryonic development and tissue patterning. It functions by interacting with Wnt signaling components, thereby influencing cell fate determination and differentiation processes.
The antibody's ability to target NKD1 enables researchers to investigate its role in various biological processes, such as cell proliferation, migration, and morphogenesis.Given the importance of the Wnt signaling pathway in cancer development and stem cell function, studying NKD1's impact on these processes is essential for advancing our understanding of disease progression and potential therapeutic interventions. The NKD1 Rabbit Polyclonal Antibody provides a valuable tool for exploring the intricate mechanisms by which NKD1 contributes to normal and pathological cellular functions.
Product Name:
NKD1 Rabbit Polyclonal Antibody
SKU:
CAB17799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKD1 (NP_149110.1).
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Purification Method:
Affinity purification
Gene ID:
85407
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NKD1 Rabbit pAb (CAB17799) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
