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NIT2 Antibody (PACO41682)

SKU:
PACO41682
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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NIT2 Antibody (PACO41682)

The Nit2 Polyclonal Antibody (PAC041682) is a valuable tool for research involving Nit2, a protein involved in various biological processes. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. Nit2, also known as Nitrf, is a protein that plays a critical role in regulating cellular metabolism and response to oxidative stress. Its functions in energy metabolism and antioxidant defense make it a key target for studies in areas such as metabolism, aging, and neurodegenerative diseases.

By specifically binding to Nit2 protein, this antibody allows for the detection and analysis of Nit2 in different cell types, providing valuable insights into its role in cellular processes. Researchers in fields such as biochemistry, molecular biology, and medicine will find this antibody essential for their studies on Nit2 and its implications in various biological pathways.

Antibody Name:NIT2 Antibody (PACO41682)
Antibody SKU:PACO41682
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:Human, Mouse
Immunogen:Recombinant Human Omega-amidase NIT2 protein (1-276AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot. All lanes: NIT2 antibody at 3µg/ml. Lane 1: Mouse heart tissue. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa.
Background:Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Synonyms:Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2), NIT2
UniProt Protein Function:NIT2: a protein of unknown function. A CN hydrolase domain suggests that this protein may be involved in nitrilase-related metabolism and handling.
UniProt Protein Details:

Protein type:EC 3.5.1.3; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 3q12.2

Cellular Component: centrosome; mitochondrion; cytoplasm

Molecular Function:omega-amidase activity

Biological Process: oxaloacetate metabolic process; glutamine metabolic process; asparagine metabolic process

UniProt Code:Q9NQR4
NCBI GenInfo Identifier:74725271
NCBI Gene ID:56954
NCBI Accession:Q9NQR4.1
UniProt Secondary Accession:Q9NQR4,Q8WUF0, B2R9A3, D3DN47,
UniProt Related Accession:Q9NQR4
Molecular Weight:276
NCBI Full Name:Omega-amidase NIT2
NCBI Synonym Full Names:nitrilase family, member 2
NCBI Official Symbol:NIT2  
NCBI Official Synonym Symbols:HEL-S-8a  
NCBI Protein Information:omega-amidase NIT2; Nit protein 2; nitrilase homolog 2; epididymis secretory sperm binding protein Li 8a
UniProt Protein Name:Omega-amidase NIT2
UniProt Synonym Protein Names:Nitrilase homolog 2
Protein Family:Nitrilase
UniProt Gene Name:NIT2  
UniProt Entry Name:NIT2_HUMAN
Antibodies
NIT2 Antibody (PACO10860)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

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