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NIT2 Antibody (PACO10860)

SKU:
PACO10860
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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NIT2 Antibody (PACO10860)

The NIT2 Polyclonal Antibody (PACO10860) is a valuable tool for researchers studying NIT2, a key enzyme involved in nitrogen metabolism and cellular energy production. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the NIT2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in biochemistry and metabolism research.NIT2, also known as nitrilase homolog 2, plays a crucial role in maintaining cellular nitrogen balance and energy homeostasis by catalyzing the conversion of toxic nitriles into useful amino acids.

The importance of NIT2 in metabolic pathways makes it a promising target for investigating diseases related to nitrogen metabolism dysregulation, such as metabolic disorders and certain cancers. A thorough understanding of NIT2 function is essential for developing targeted therapies that address these conditions at the molecular level.

Antibody Name:NIT2 Antibody (PACO10860)
Antibody SKU:PACO10860
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human NIT2
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:nitrilase family, member 2;NIT2;MGC111199 ;
UniProt Protein Function:NIT2: a protein of unknown function. A CN hydrolase domain suggests that this protein may be involved in nitrilase-related metabolism and handling.
UniProt Protein Details:

Protein type:EC 3.5.1.3; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 3q12.2

Cellular Component: centrosome; mitochondrion; cytoplasm

Molecular Function:omega-amidase activity

Biological Process: oxaloacetate metabolic process; glutamine metabolic process; asparagine metabolic process

UniProt Code:Q9NQR4
NCBI GenInfo Identifier:74725271
NCBI Gene ID:56954
NCBI Accession:Q9NQR4.1
UniProt Secondary Accession:Q9NQR4,Q8WUF0, B2R9A3, D3DN47,
UniProt Related Accession:Q9NQR4
Molecular Weight:276
NCBI Full Name:Omega-amidase NIT2
NCBI Synonym Full Names:nitrilase family, member 2
NCBI Official Symbol:NIT2  
NCBI Official Synonym Symbols:HEL-S-8a  
NCBI Protein Information:omega-amidase NIT2; Nit protein 2; nitrilase homolog 2; epididymis secretory sperm binding protein Li 8a
UniProt Protein Name:Omega-amidase NIT2
UniProt Synonym Protein Names:Nitrilase homolog 2
Protein Family:Nitrilase
UniProt Gene Name:NIT2  
UniProt Entry Name:NIT2_HUMAN

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