The NIPSNAP1 Polyclonal Antibody (CAB17951) is a valuable tool for researchers studying NIPSNAP1, a protein involved in mitochondrial dynamics and intracellular trafficking. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it suitable for use in various applications, including Western blot and immunofluorescence. By binding to NIPSNAP1, this antibody allows for the detection and analysis of this protein in different cell types, providing insight into its role in cellular processes.NIPSNAP1 is known to play a crucial role in mitochondrial function and morphology, making it an essential target for research in the fields of cell biology and metabolism.
Dysfunction in mitochondrial dynamics has been linked to various diseases, including neurodegenerative disorders and metabolic conditions. Therefore, studying the function of NIPSNAP1 can help uncover potential therapeutic targets for these diseases and contribute to our understanding of cellular homeostasis.Overall, the NIPSNAP1 Polyclonal Antibody is a reliable tool for investigating the function of NIPSNAP1 and its impact on cellular processes, making it an invaluable resource for researchers interested in mitochondrial biology and related diseases.
Product Name:
NIPSNAP1 Rabbit Polyclonal Antibody
SKU:
CAB17951
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-145 of human NIPSNAP1 (NP_003625.2).
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8508
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NIPSNAP1 antibody (CAB17951) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
