The NINJ2 Polyclonal Antibody (PAC042002) is a vital tool for researchers studying NINJ2, a protein involved in neuronal development and regeneration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot experiments. By binding to the NINJ2 protein, this antibody enables precise detection and analysis in various cell types, facilitating studies in neuroscience and regenerative medicine.NINJ2, also known as a neurotrophin receptor p75, plays a crucial role in promoting axon growth and neuronal survival, making it a promising target for research on neurodegenerative diseases and nerve regeneration therapies.
Understanding the function of NINJ2 is essential for developing innovative treatments for conditions such as Alzheimer's disease, stroke, and spinal cord injuries. Researchers can leverage the NINJ2 Polyclonal Antibody to unravel the intricate mechanisms underlying NINJ2-mediated processes and pave the way for novel therapeutic interventions.
Immunohistochemistry of paraffin-embedded human lung tissue using PACO42002 at dilution of 1:100.
Immunofluorescent analysis of A431 cells using PACO42002 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO42002 at dilution of 1:100.
Background:
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues.
Synonyms:
Ninjurin-2 (Nerve injury-induced protein 2), NINJ2
UniProt Protein Function:
NINJ2: Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Belongs to the ninjurin family.Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 12p13.33Cellular Component: integral component of plasma membraneMolecular Function: protein bindingBiological Process: nervous system development; neuron adhesion; tissue regeneration
