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NINJ1 Monoclonal Antibody

SKU:
CAB24739
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
IF
$167 - $635
Frequently bought together:

Description

NINJ1 Monoclonal Antibody (CAB24739)

The NINJ1 Monoclonal Antibody is a highly specific tool for researchers studying the NINJ1 protein, a key player in the process of axon regeneration. This antibody, generated using state-of-the-art techniques, is ideal for various immunological and neurological studies, particularly in the fields of nerve regeneration and neural injury.NINJ1, also known as Ninjurin-1, is a cell surface protein that has been shown to promote axonal growth and regeneration after injury. By targeting NINJ1 with this monoclonal antibody, researchers can accurately detect and analyze the protein in a variety of cell types, shedding light on its functions and potential therapeutic applications.

This monoclonal antibody is validated for use in Western blotting applications, ensuring reliable and reproducible results. Its high specificity and sensitivity make it a valuable tool for investigating the role of NINJ1 in neurological disorders, nerve injuries, and regenerative medicine. By understanding the mechanisms underlying NINJ1 function, researchers can develop novel strategies for promoting nerve regeneration and recovery in patients.

Product Name:NINJ1 Monoclonal Antibody
Product Code:CAB24739
Reactivity:Mouse, Rat
Applications:Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC63467
Reactivity:Mouse, Rat
Tested Applications:IHC-P, IF/ICC, ELISA
Key Applications:Immunohistochemistry, Immunofluorescence
Recommended Dilution:IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Membrane, Multi-pass membrane protein

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NINJ1 (NP_004139.2).
Sequence:MDSGT EEYEL NGGLP PGTPG SPDAS PARWG WRHGP INVNH YASKK SAAES MLDIA LLMAN ASQLK AVVEQ GPSFA FYVPL VVLIS ISLVL QIGVG VLLIF
Synonyms:NIN1, NINJURIN
Calculated MW:16kDa
Observed MW:Refer to figures

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