NINJ1 Monoclonal Antibody
- SKU:
- CAB24739
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- IF
Description
NINJ1 Monoclonal Antibody (CAB24739)
The NINJ1 Monoclonal Antibody is a highly specific tool for researchers studying the NINJ1 protein, a key player in the process of axon regeneration. This antibody, generated using state-of-the-art techniques, is ideal for various immunological and neurological studies, particularly in the fields of nerve regeneration and neural injury.NINJ1, also known as Ninjurin-1, is a cell surface protein that has been shown to promote axonal growth and regeneration after injury. By targeting NINJ1 with this monoclonal antibody, researchers can accurately detect and analyze the protein in a variety of cell types, shedding light on its functions and potential therapeutic applications.
This monoclonal antibody is validated for use in Western blotting applications, ensuring reliable and reproducible results. Its high specificity and sensitivity make it a valuable tool for investigating the role of NINJ1 in neurological disorders, nerve injuries, and regenerative medicine. By understanding the mechanisms underlying NINJ1 function, researchers can develop novel strategies for promoting nerve regeneration and recovery in patients.
Product Name: | NINJ1 Monoclonal Antibody |
Product Code: | CAB24739 |
Reactivity: | Mouse, Rat |
Applications: | Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC63467 |
Reactivity: | Mouse, Rat |
Tested Applications: | IHC-P, IF/ICC, ELISA |
Key Applications: | Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Membrane, Multi-pass membrane protein |
The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NINJ1 (NP_004139.2). |
Sequence: | MDSGT EEYEL NGGLP PGTPG SPDAS PARWG WRHGP INVNH YASKK SAAES MLDIA LLMAN ASQLK AVVEQ GPSFA FYVPL VVLIS ISLVL QIGVG VLLIF |
Synonyms: | NIN1, NINJURIN |
Calculated MW: | 16kDa |
Observed MW: | Refer to figures |