NHP2 Rabbit Polyclonal Antibody (CAB5991)
- SKU:
- CAB5991
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NHP2 Rabbit Polyclonal Antibody |
SKU: | CAB5991 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human NHP2 (NP_060308.1). |
Sequence: | MTKI KADP DGPE AQAE ACSG ERTY QELL VNQN PIAQ PLAS RRLT RKLY KCIK KAVK QKQI RRGV KEVQ KFVN KGEK GIMV LAGD TLPI EVYC HLPV MCED RNLP YVYI PSKT DLGA AAGS KRPT CVIM VKPH EEYQ EAYD ECLE EVQS LPLP L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DKCB2; NHP2P; NOLA2; NHP2 |
Positive Sample: | 293T,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cajal body, Nucleus, nucleolus. |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55651 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |