The NHLRC2 Polyclonal Antibody (PACO39686) is a valuable tool for researchers studying NHLRC2, a protein involved in autophagy, lysosomal degradation, and neurodegenerative disorders. This antibody is produced using rabbits and has high reactivity with human samples, making it suitable for Western blot applications. By binding to the NHLRC2 protein, researchers can detect and analyze the protein in various cell types, making it an ideal choice for studies in neuroscience and neurology.
NHLRC2, also known as EPM2AIP1, is an important player in the autophagy pathway, helping to remove damaged proteins and organelles from cells. Dysregulation of autophagy has been implicated in various neurodegenerative diseases such as Parkinson's and Alzheimer's, making NHLRC2 a promising target for further research. By understanding the role of NHLRC2 in these conditions, researchers may uncover new therapeutic strategies for treating these debilitating diseases.
Western blot. All lanes: NHLRC2 antibody at 8µg/ml + U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 80, 40 kDa. Observed band size: 80 kDa.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO39686 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO39686 at dilution of 1:100.
Synonyms:
NHL repeat-containing protein 2, NHLRC2
UniProt Protein Function:
NHLRC2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 10q25.3Molecular Function: protein binding