NHLRC1 Rabbit Polyclonal Antibody (CAB6669)
- SKU:
- CAB6669
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | NHLRC1 Rabbit Polyclonal Antibody |
SKU: | CAB6669 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NHLRC1 (NP_940988.2). |
Sequence: | MAAE ASES GPAL HELM REAE ISLL ECKV CFEK FGHR QQRR PRNL SCGH VVCL ACVA ALAH PRTL ALEC PFCR RACR GCDT SDCL PVLH LIEL LGSA LRQS PAAH RAAP SAPG ALTC HHTF GGWG TLVN PTGL ALCP KTGR VVVV HDGR RRVK IFDS GGGC AHQF GEKG DAAQ DIRY PVDV TITN DCHV VVTD AGDR SIKV FDFF GQIK LVIG GQFS LPWG VETT PQNG IVVT DAEA GSLH LLDV DFAE GVLR RTER LQAH LCNP RGVA VSWL TGAI AVLE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:2000 - 1:7000 IHC-P,1:50 - 1:200 |
Synonyms: | EPM2A; EPM2B; MALIN; bA204B7.2; NHLRC1 |
Positive Sample: | Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa/45kDa |
The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).
Purification Method: | Affinity purification |
Gene ID: | 378884 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |