The NGLY1 Polyclonal Antibody (CAB15864) is a valuable tool for researchers studying NGLY1, a gene associated with a rare genetic disorder called NGLY1 deficiency. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the NGLY1 protein, enabling precise detection and analysis in a variety of cell types.NGLY1 deficiency is a complex disease that affects multiple systems in the body, including the nervous system and liver.
Research into this disorder is crucial for understanding its underlying mechanisms and developing potential treatments. The NGLY1 Polyclonal Antibody offers researchers a reliable means of studying NGLY1 protein expression and function, facilitating progress in the field of rare genetic disorders and potentially leading to advancements in therapeutic strategies.
Product Name:
NGLY1 Rabbit Polyclonal Antibody
SKU:
CAB15864
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NGLY1 (NP_060767.2).
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55768
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NGLY1 antibody (CAB15864) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
