The NGFR Rabbit Monoclonal Antibody (CAB19088) is a highly specific antibody designed for research involving the nerve growth factor receptor (NGFR), also known as CD271. NGFR is a cell surface protein involved in cell differentiation, survival, and apoptosis in the nervous system.This antibody, generated in rabbits, is reactive with human samples and has been validated for use in various applications, including immunohistochemistry, flow cytometry, and Western blot. By binding to NGFR, this antibody enables accurate detection and analysis of NGFR expression in different cell types, making it an essential tool for studies in neuroscience, neurobiology, and cancer research.
The nerve growth factor receptor is a crucial marker for various cell types, including neural stem cells and some cancer stem cells, making it a valuable target for understanding neurogenesis, neuronal development, and tumor progression. By studying the expression and function of NGFR, researchers can gain insights into neurodegenerative diseases, nerve regeneration, and cancer therapy development.
Product Name:
NGFR Rabbit Monoclonal Antibody
SKU:
CAB19088
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human p75 NGF Receptor (P08138).
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Purification Method:
Affinity purification
Gene ID:
4804
Clone Number:
ARC0284
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using p75NTR/NGFR Rabbit mAb (CAB19088) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
