The NGFR Polyclonal Antibody (CAB2097) is a valuable tool for research involving NGFR, a protein known as the nerve growth factor receptor. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the NGFR protein, researchers can detect and analyze its presence in various cell types, making it ideal for studies in neuroscience, neurobiology, and regenerative medicine.NGFR is a key player in the development and maintenance of the nervous system, playing a crucial role in neuronal survival, differentiation, and growth.
Dysregulation of NGFR has been linked to various neurological disorders and neurodegenerative diseases, making it a promising target for therapeutic interventions. Understanding the function and expression of NGFR is essential for advancing research in these fields and developing novel treatments for neurological conditions.
Product Name:
NGFR Rabbit Polyclonal Antibody
SKU:
CAB2097
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 301-400 of human p75NTR/NGFR (NP_002498.1).
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Purification Method:
Affinity purification
Gene ID:
4804
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat spleen using p75NTR/NGFR Rabbit pAb(CAB2097) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:30s.
