The NGFR Polyclonal Antibody (CAB11169) is a valuable tool for researchers studying nerve growth factor receptor (NGFR), a cell surface protein involved in the regulation of neuronal development and function. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to NGFR, researchers can accurately detect and analyze this important protein in a variety of cell types, making it ideal for studies in neurobiology and nerve regeneration research.NGFR plays a crucial role in neuronal survival, differentiation, and growth, making it a key player in development and maintenance of the nervous system.
Researchers studying neurological disorders, including Alzheimer's disease, Parkinson's disease, and spinal cord injuries, can benefit from using this antibody to investigate the function and expression of NGFR in different cellular contexts. Understanding the role of NGFR in these conditions can lead to the development of novel therapeutic strategies targeting this receptor for potential treatment options.
Product Name:
NGFR Rabbit Polyclonal Antibody
SKU:
CAB11169
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 273-427 of human p75NTR/NGFR (NP_002498.1).
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Purification Method:
Affinity purification
Gene ID:
4804
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB11169) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
