The NGF Polyclonal Antibody (CAB13922) is a valuable tool for researchers studying nerve growth factor (NGF), a protein involved in the growth, survival, and maintenance of nerve cells. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in various applications such as Western blot and immunohistochemistry.NGF is a key player in the development and function of the nervous system, making it a crucial target for studies in neurobiology, neurodegenerative diseases, and pain research. By specifically binding to NGF, this antibody allows for precise detection and analysis of NGF levels in different cell types and tissues, providing valuable insights into the role of NGF in various biological processes.
The NGF Polyclonal Antibody is a reliable tool for researchers looking to investigate the function and regulation of NGF in both health and disease. Its high specificity and sensitivity make it an ideal choice for studies aimed at uncovering the mechanisms underlying neurological disorders and identifying potential therapeutic targets for these conditions.
Product Name:
NGF Rabbit Polyclonal Antibody
SKU:
CAB13922
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-241 of human NGF (NP_002497.2).
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Purification Method:
Affinity purification
Gene ID:
4803
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using NGF Rabbit pAb (CAB13922) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
