The NGDN Polyclonal Antibody (CAB14546) is a versatile research tool designed for studying NGDN, a protein involved in neural development and regeneration. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to NGDN, allowing for accurate detection and analysis in a variety of cell types.NGDN, also known as Neural Guidance Cue Downregulated by Neuroserpin, is a crucial player in the guidance of neuronal growth cones during development. Its role in promoting axon regeneration after injury has sparked interest in its potential therapeutic applications for nerve damage and neurodegenerative disorders.
Research into the mechanisms of NGDN function is essential for advancing our understanding of neural regeneration and developing new treatments for neurological conditions. In conclusion, the NGDN Polyclonal Antibody is an excellent tool for investigating the functions of NGDN in various biological contexts. Its high specificity and reliability make it a valuable asset for researchers in the fields of neuroscience, neurology, and regenerative medicine.
Product Name:
NGDN Rabbit Polyclonal Antibody
SKU:
CAB14546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-209 of human NGDN (NP_001036100.1).
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).
Purification Method:
Affinity purification
Gene ID:
25983
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NGDN Rabbit pAb (CAB14546) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
