The NGDN Polyclonal Antibody (CAB14509) is a valuable tool for researchers studying NGDN, a protein involved in neurological development and disease. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.NGDN, or Noggin, is a secreted protein that plays a critical role in regulating the growth and development of nerve cells in the brain. Dysregulation of NGDN has been implicated in neurological disorders such as Alzheimer's disease, Parkinson's disease, and autism spectrum disorders.
By using the NGDN Polyclonal Antibody, researchers can detect and study the expression levels of NGDN in different cell types, providing valuable insights into its function and potential therapeutic applications.With its high reactivity and specificity, the NGDN Polyclonal Antibody is an essential tool for researchers working in the fields of neuroscience, neurology, and developmental biology. Understanding the role of NGDN in neurological development and disease could lead to new treatment strategies and interventions for a range of disorders affecting the central nervous system.
Product Name:
NGDN Rabbit Polyclonal Antibody
SKU:
CAB14509
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-209 of human NGDN (NP_001036100.1).
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).
Purification Method:
Affinity purification
Gene ID:
25983
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NGDN Rabbit pAb (CAB14509) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
