The NG2/CSPG4 Polyclonal Antibody (CAB21815) is a valuable tool for researchers studying the NG2/CSPG4 protein, which is known for its role in various cellular processes such as cell proliferation, migration, and adhesion. This antibody, generated in rabbits, exhibits strong reactivity with human samples, making it suitable for use in Western blot applications.NG2/CSPG4, a cell surface chondroitin sulfate proteoglycan, is implicated in cancer progression and metastasis, as well as in the regulation of stem cell function. Its expression has been linked to various cancer types, making it an attractive target for cancer research.
The NG2/CSPG4 Polyclonal Antibody allows for the detection and analysis of the protein in different cell types, providing valuable insights into its function and potential therapeutic implications.By understanding the role of NG2/CSPG4 in cancer biology and other cellular processes, researchers can uncover new therapeutic targets and develop novel treatments for cancer and other related diseases. The NG2/CSPG4 Polyclonal Antibody is a crucial tool for advancing research in this area and uncovering the potential clinical applications of targeting this protein.
Product Name:
NG2/CSPG4 Polyclonal Antibody
SKU:
CAB21815
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1950-2210 of human NG2/CSPG4 (NP_001888.2).
Apical cell membrane, Cell projection, Extracellular side, Single-pass type I membrane protein, lamellipodium membrane.
Calculated MW:
251kDa
Observed MW:
250-450kDa
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Purification Method:
Affinity purification
Gene ID:
1464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-138 MG cells, using NG2/CSPG4 Rabbit pAb (CAB21815) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
