The NFYC Polyclonal Antibody (CAB9832) is a vital tool for researchers studying NFYC, a transcription factor that plays a key role in regulating gene expression and cell growth. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.NFYC is involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. By targeting the NFYC protein, this antibody allows for the detection and analysis of NFYC expression in different cell types, making it ideal for studies in molecular biology and cancer research.
The NFYC Polyclonal Antibody is particularly valuable for investigating the role of NFYC in cancer progression and metastasis, as well as its potential as a therapeutic target. Understanding the function of NFYC is crucial for developing targeted therapies that can effectively inhibit or enhance its activity in the context of cancer and other diseases.
Product Name:
NFYC Rabbit Polyclonal Antibody
SKU:
CAB9832
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-120 of human NFYC (NP_055038.2).
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4802
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Rat thymus, using NFYC antibody (CAB9832) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
