NFYB Rabbit Polyclonal Antibody (CAB7295)
- SKU:
- CAB7295
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NFYB Rabbit Polyclonal Antibody |
SKU: | CAB7295 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human NFYB (NP_006157.1). |
Sequence: | MTMD GDSS TTDA SQLG ISAD YIGG SHYV IQPH DDTE DSMN DHED TNGS KESF REQD IYLP IANV ARIM KNAI PQTG KIAK DAKE CVQE CVSE FISF ITSE ASER CHQE KRKT INGE DILF AMST LGFD SYVE PLKL YLQK FREA MKGE KGIG GAVT ATDG LSEE LTEE AFTN QLPA GLIT TDGQ QQNV MVYT TSYQ QISG VQQI QFS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HAP3; CBF-A; CBF-B; NF-YB; NFYB |
Positive Sample: | HL-60,SKOV3,HeLa,Mouse liver,Mouse spleen,Mouse brain,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 28-30kDa |
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
Purification Method: | Affinity purification |
Gene ID: | 4801 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |