NFKBIZ Rabbit Polyclonal Antibody (CAB10492)
- SKU:
- CAB10492
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NFKBIZ Rabbit Polyclonal Antibody |
SKU: | CAB10492 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFKBIZ (NP_113607.1). |
Sequence: | MIVD KLLD DSRG GEGL RDAA GGCG LMTS PLNL SYFY GASP PAAA PGAC DASC SVLG PSAP GSPG SDSS DFSS ASSV SSCG AVES RSRG GARA ERQP VEPH MGVG RQQR GPFQ GVRV KNSV KELL LHIR SHKQ KASG QAVD DFKT QGVN IEQF RELK NTVS YSGK RKGP DSLS DGPA CKRP ALLH SQFL TPPQ TPTP GESM EDVH LNEP KQES SADL LQNI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | IKBZ; INAP; MAIL; ikB-zeta; ikappaBzeta; IkappaB-zeta; I-kappa-B-zeta; NFKBIZ |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 78kDa |
Observed MW: | 64kDa |
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 64332 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |