NFKBID Antibody (PACO39170)
- SKU:
- PACO39170
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
NFKBID Antibody (PACO39170)
The NFKBID Polyclonal Antibody (PAC039170) is an essential tool for research involving NFKBID, a key regulator of the NF-kappa-B signaling pathway. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it a reliable option for Western blot applications. By binding to the NFKBID protein, researchers can detect and analyze its expression in various cell types, facilitating studies in immunology and cancer research.NFKBID, also known as NF-kappa-B inhibitor delta, plays a crucial role in modulating the NF-kappa-B pathway, which is involved in immune and inflammatory responses.
By inhibiting NF-kappa-B activation, NFKBID helps regulate the expression of pro-inflammatory genes, making it a promising target for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. Research on NFKBID is essential for uncovering new therapeutic strategies that can manipulate immune responses for therapeutic benefit.
| Antibody Name: | NFKBID Antibody (PACO39170) |
| Antibody SKU: | PACO39170 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human NF-kappa-B inhibitor delta protein (1-150AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate. All lanes: NFKBID antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 34, 51, 16 kDa. Observed band size: 34 kDa. |
| Background: | May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes. |
| Synonyms: | NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH), NFKBID, IKBNS |
| UniProt Protein Function: | NFKBID: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR- induced negative selection of thymocytes. Belongs to the NF-kappa-B inhibitor family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: nucleus Molecular Function:NF-kappaB binding Biological Process: inhibition of NF-kappaB transcription factor; negative regulation of T cell differentiation in the thymus; negative regulation of I-kappaB kinase/NF-kappaB cascade; inflammatory response |
| UniProt Code: | Q8NI38 |
| NCBI GenInfo Identifier: | 74751323 |
| NCBI Gene ID: | 84807 |
| NCBI Accession: | Q8NI38.1 |
| UniProt Secondary Accession: | Q8NI38,Q8NI39, Q9BRG9, |
| UniProt Related Accession: | Q8NI38 |
| Molecular Weight: | 150 |
| NCBI Full Name: | NF-kappa-B inhibitor delta |
| NCBI Synonym Full Names: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta |
| NCBI Official Symbol: | NFKBIDÂ Â |
| NCBI Official Synonym Symbols: | TA-NFKBH; IkappaBNSÂ Â |
| NCBI Protein Information: | NF-kappa-B inhibitor delta; ikB-delta; ikappaBdelta; I-kappa-B-delta; T-cell activation NFKB-like protein |
| UniProt Protein Name: | NF-kappa-B inhibitor delta |
| UniProt Synonym Protein Names: | I-kappa-B-delta; IkB-delta; IkappaBdelta; IkappaBNS; T-cell activation NFKB-like protein; TA-NFKBH |
| Protein Family: | NF-kappa-B inhibitor |
| UniProt Gene Name: | NFKBIDÂ Â |
| UniProt Entry Name: | IKBD_HUMAN |
Related Products
NFKBID Antibody (PACO13939)
NFKBID Antibody (PACO13938)
ompF Antibody (PACO64865)
ANKEF1 Antibody (PACO64597)
CYP2A13 Antibody (PACO64657)
HNR Antibody Antibody (CAB17497)
