The NFIL3 Polyclonal Antibody (CAB14029) is a valuable tool for researchers studying NFIL3, a transcription factor that plays a crucial role in regulating immune responses and circadian rhythm. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of applications including Western blot, immunofluorescence, and immunoprecipitation.NFIL3, also known as E4BP4, is involved in the regulation of genes that control immune cell development and function. It has been implicated in various diseases including cancer, autoimmune disorders, and inflammatory conditions.
Understanding the function of NFIL3 is essential for developing targeted therapies that modulate immune responses in these disease contexts.With the NFIL3 Polyclonal Antibody, researchers can effectively detect and analyze NFIL3 expression in different cell types, providing valuable insights into its role in immune regulation and disease pathogenesis. This antibody is a key tool for advancing our understanding of NFIL3 and its potential as a therapeutic target in various immunological and pathological conditions.
Product Name:
NFIL3 Rabbit Polyclonal Antibody
SKU:
CAB14029
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 133-462 of human NFIL3 (NP_005375.2).
The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using NFIL3 antibody (CAB14029) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
