The NFE2L1 Polyclonal Antibody (CAB14753) is a valuable tool for researchers studying NFE2L1, a transcription factor that plays a key role in regulating oxidative stress responses. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. By binding specifically to the NFE2L1 protein, researchers can accurately detect and analyze its expression in various cell types, making it a valuable tool for studies in fields such as oxidative stress, metabolism, and aging.
NFE2L1, also known as Nrf1, is a critical regulator of cellular responses to oxidative stress and plays a vital role in maintaining cellular homeostasis. Dysregulation of NFE2L1 has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. By studying the activity of NFE2L1 using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
NFE2L1 Rabbit Polyclonal Antibody
SKU:
CAB14753
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 515-772 of human NFE2L1 (NP_003195.1).
Endoplasmic reticulum membrane, Nucleus, Single-pass type II membrane protein.
Calculated MW:
85kDa
Observed MW:
120kDa
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1.
Purification Method:
Affinity purification
Gene ID:
4779
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NFE2L1 Rabbit pAb (CAB14753) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
