The NFATC3 Polyclonal Antibody (CAB6666) is a specialized tool for researchers investigating NFATC3, a key transcription factor involved in regulating gene expression in immune cells. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the NFATC3 protein, this antibody enables precise detection and analysis in various cell types, making it an essential asset for studies in immunology and cancer research.NFATC3 is a crucial player in immune responses, serving as a key mediator in the activation of T cells and B cells.
Its role in coordinating the expression of genes involved in immune function highlights its importance in understanding the mechanisms underlying immune system regulation. Research on NFATC3 is particularly relevant in the context of diseases such as cancer, autoimmune disorders, and inflammatory conditions, where aberrant immune responses can contribute to pathology. By elucidating the functions of NFATC3, researchers can pave the way for developing targeted therapies that manipulate immune responses for therapeutic benefit.
Product Name:
NFATC3 Rabbit Polyclonal Antibody
SKU:
CAB6666
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NFATC3 (NP_775188.1).
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
4775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NFATC3 Rabbit pAb (CAB6666) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
