The NFATC2 Polyclonal Antibody (CAB14189) is a powerful tool for researchers studying NFATC2, a key transcription factor involved in immune response and cell development. This antibody, produced in rabbits, has high specificity and sensitivity for detecting NFATC2 in human samples, making it ideal for use in Western blot experiments. By targeting the NFATC2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it essential for studies in immunology, cancer research, and cell signaling pathways.NFATC2, also known as Nuclear Factor of Activated T cells 2, plays a crucial role in regulating gene expression in response to various stimuli, including immune activation and cellular stress.
Understanding the function of NFATC2 is crucial for unraveling its role in immune system regulation, and its dysregulation has been associated with various diseases, including cancer, autoimmune disorders, and inflammatory conditions. By using the NFATC2 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for treatment.
Product Name:
NFATC2 Rabbit Polyclonal Antibody
SKU:
CAB14189
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2 (NP_775114.1).
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Purification Method:
Affinity purification
Gene ID:
4773
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NFATC2 antibody (CAB14189) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
