NFATC2 Rabbit Polyclonal Antibody (CAB14189)
- SKU:
- CAB14189
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NFATC2 Rabbit Polyclonal Antibody |
SKU: | CAB14189 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NFATC2 (NP_775114.1). |
Sequence: | MNAP ERQP QPDG GDAP GHEP GGSP QDEL DFSI LFDY EYLN PNEE EPNA HKVA SPPS GPAY PDDV LDYG LKPY SPLA SLSG EPPG RFGE PDRV GPQK FLSA AKPA GASG LSPR IEIT PSHE LIQA VGPL RMRD AGLL VEQP PLAG VAAS PRFT LPVP GFEG YREP LCLS PASS GSSA SFIS DTFS PYTS PCVS PNNG GPDD LCPQ FQNI PAHY SPRT SPIM SPRT SLAE DSCL GRHS PVPR PASR SSSP GAKR RHSC AEAL VALP PGAS PQRS RSPS PQPS SHVA PQDH GSPA GYPP VAGS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | JCOSL; NFAT1; NFATP; NFATC2 |
Positive Sample: | Jurkat,mouse thymus,mouse spleen,rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 100kDa |
Observed MW: | 130kDa |
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 4773 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |