NFAT2 Rabbit Polyclonal Antibody (CAB16928)
- SKU:
- CAB16928
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | NFAT2 Rabbit Polyclonal Antibody |
SKU: | CAB16928 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-298 of NFAT2 (NP_001265598.1). |
Sequence: | LESP RIEI TSCL GLYH NNNQ FFHD VEVE DVLP SSKR SPST ATLS LPSL EAYR DPSC LSPA SSLS SRSC NSEA SSYE SNYS YPYA SPQT SPWQ SPCV SPKT TDPE EGFP RGLG ACTL LGSP RHSP STSP RASV TEES WLGA RSSR PASP CNKR KYSL NGRQ PPYS PHHS PTPS PHGS PRVS VTDD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | NFAT2; NFATc; NF-ATC; NF-ATc1.2 |
Positive Sample: | 293T,U-87MG,K-562 |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 101kDa |
Observed MW: | 75-100kDa |
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Purification Method: | Affinity purification |
Gene ID: | 4772 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |