NFAT2 Rabbit Polyclonal Antibody (CAB1539)
- SKU:
- CAB1539
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | NFAT2 Rabbit Polyclonal Antibody |
SKU: | CAB1539 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of NFAT2 (NP_765978.1). |
Sequence: | VFGR GETL GPAP RAGG TMKS AEEE HYGY ASSN VSPA LPLP TAHS TLPA PCHN LQTS TPGI IPPA DHPS GYGA ALDG GPAG YFLS SGHT RPDG APAL ESPR IEIT SCLG LYHN NNQF FHDV EVED VLPS SKRS PSTA TLSL PSLE AYRD PSCL SPAS SLSS RSCN SEAS SYES NYSY PYAS PQTS PWQS PCVS PKTT DPEE GFPR GLGA CTLL GSPR HSPS TSPR ASVT EESW LGAR SSRP ASPC NKRK YSLN GRQP PYSP HHSP TPSP HGSP RVSV TDDS W |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NFAT2; NFATc; NF-ATC; NF-ATc1.2 |
Positive Sample: | Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 101kDa |
Observed MW: | 101kDa |
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Purification Method: | Affinity purification |
Gene ID: | 4772 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |