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NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)

SKU:
CPAB0566
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT1C3AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)

The NFATc1 Polyclonal Antibody (CPAB0566) is a vital tool for researchers studying NFATc1, a key transcription factor involved in immune cell activation and differentiation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, and is validated for use in Western blot applications.NFATc1 plays a pivotal role in mediating immune responses, particularly in T cells and B cells. It is a critical regulator of cytokine production, proliferation, and differentiation of immune cells, making it a target of interest in immunology and cancer research.

By targeting NFATc1, researchers can gain insights into various immune processes and potentially develop targeted therapies for immune-related disorders and cancers.With its ability to detect NFATc1 protein in different cell types, the NFATc1 Polyclonal Antibody is an invaluable tool for studying the role of NFATc1 in immune regulation and disease pathogenesis. Researchers can use this antibody to further understand the mechanisms underlying immune cell function and explore potential therapeutic interventions in various immune-related conditions.

Product Name:NFATC1 Antibody
Product Sku:CPAB0566
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NFATC1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NFATC1 amino acids 428-716 purified from Ecoli.
Clone:PAT1C3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:NFATC1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least 2 components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play an essential role in inducible gene transcription during immune response. NFATC1 is an inducible nuclear component. NFATC1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of NFATC1 may regulate inducible expression of different cytokine genes.
Synonyms:Nuclear factor of activated T-cells cytoplasmic 1, NFAT transcription complex cytosolic component, NF-ATc1, NFATc1, NF-ATc, NFATc, NFAT2, MGC138448.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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