The NFAT5 Polyclonal Antibody (CAB16649) is a valuable tool for researchers studying NFAT5, a transcription factor involved in osmoregulation and immune responses. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications.NFAT5, also known as TonEBP, plays a crucial role in regulating cellular responses to changes in osmolarity and stress, as well as mediating inflammatory processes. Its involvement in immune cell function and the pathogenesis of diseases such as cancer and autoimmune disorders makes it an important target for drug development and therapeutic interventions.
By utilizing the NFAT5 Polyclonal Antibody, researchers can accurately detect and quantify NFAT5 expression in various cell types, aiding in the understanding of its biological functions and potential as a therapeutic target. This antibody is a valuable tool for studies in immunology, oncology, and other fields exploring the role of NFAT5 in health and disease.
Product Name:
NFAT5 Rabbit Polyclonal Antibody
SKU:
CAB16649
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1355-1455 of human NFAT5 (NP_619728.2).
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10725
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NFAT5 Rabbit pAb (CAB16649) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
