The NFAT2 Monoclonal Antibody is a valuable tool for studying NFAT2, a transcription factor that plays a crucial role in the immune response and T cell activation. This antibody, produced using monoclonal antibody technology, is highly specific for NFAT2 and has been validated for use in various research applications, including Western blotting and immunofluorescence.NFAT2 is known to regulate the expression of genes involved in immune cell activation and differentiation, making it a key player in the immune system. By targeting NFAT2 with this antibody, researchers can delve into the mechanisms underlying immune cell function and potentially uncover new therapeutic targets for immune-mediated diseases such as autoimmune disorders and inflammatory conditions.
With its high specificity and reliability, the NFAT2 Monoclonal Antibody is a valuable tool for scientists studying immune regulation and T cell signaling pathways. Its versatility in different research applications makes it an indispensable resource for advancing our understanding of the immune system and developing new treatments for various immune-related disorders.
Product Name:
NFAT2 Monoclonal Antibody
SKU:
CAB23485
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-305 of human NFAT2 (NP_001265598.1).
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Purification Method:
Affinity purification
Gene ID:
4772
Clone Number:
ARC57041
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NFAT2 Rabbit mAb (CAB23485) at 1:7000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
