NFAT2 Monoclonal Antibody (CAB23485)
- SKU:
- CAB23485
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | NFAT2 Monoclonal Antibody |
SKU: | CAB23485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-305 of human NFAT2 (NP_001265598.1). |
Sequence: | SKFP LGPA AAVF GRGE TLGP APRA GGTM KSAE EEHY GYAS SNVS PALP LPTA HSTL PAPC HNLQ TSTP GIIP PADH PSGY GAAL DGGP AGYF LSSG HTRP DGAP ALES PRIE ITSC LGLY HNNN QFFH DVEV EDVL PSSK RSPS TATL SLPS LEAY RDPS CLSP ASSL SSRS CNSE ASSY ESNY SYPY ASPQ TSPW QSPC VSPK TTDP EEGF PRGL GACT LLGS PRHS PSTS PRAS VTEE SWLG ARSS RPAS PCNK RKYS LNGR QPPY SPHH SPTP SPHG SPRV SVTD DSWL GNTT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:8000 |
Synonyms: | NFAT2; NFATc; NF-ATC; NF-ATc1.2 |
Positive Sample: | Daudi,Jurkat,RAW 264.7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 101kDa |
Observed MW: | 75-140kDa |
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Purification Method: | Affinity purification |
Gene ID: | 4772 |
Clone Number: | ARC57041 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |