The NFAM1 Polyclonal Antibody (CAB15570) is a valuable tool for researchers studying NFAM1, a cell surface protein involved in immune signaling and lymphocyte activation. This antibody, generated in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.NFAM1, also known as nuclear factor of activated T-cells (NFAT) activating molecule 1, is a key regulator of immune responses, particularly in T cells and B cells. By binding to NFAM1, this antibody enables precise detection and analysis of NFAM1 expression in various cell types, making it an essential asset for studies in immunology and autoimmune diseases.
The role of NFAM1 in immune activation and regulation makes it an attractive target for research into diseases such as autoimmune disorders, inflammatory conditions, and infectious diseases. Understanding the function of NFAM1 is crucial for uncovering new therapeutic approaches that modulate immune responses and potentially alleviate immune-related disorders.
Product Name:
NFAM1 Rabbit Polyclonal Antibody
SKU:
CAB15570
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 186-270 of human NFAM1 (NP_666017.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
30kDa
Observed MW:
30kDa
The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells.
Purification Method:
Affinity purification
Gene ID:
150372
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse spleen, using NFAM1 Rabbit pAb (CAB15570) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
