NF-κB2 Monoclonal Antibody (CAB22279)
- SKU:
- CAB22279
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | NF-κB2 Monoclonal Antibody |
| SKU: | CAB22279 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human NF-κB2 (NP_001070962.1). |
| Sequence: | LRSL VDTY RQTT SPSG SLLR SYEL AGGD LAGL LEAL SDMG LEEG VRLL RGPE TRDK LPST AEVK EDSA YGSQ SVEQ EAEK LGPP PEPP GGLC HGHP QPQV H |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100; NF-κB2 |
| Positive Sample: | HeLa,NIH/3T3,C6 |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 97kDa |
| Observed MW: | 122kDa |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
| Purification Method: | Affinity purification |
| Gene ID: | 4791 |
| Clone Number: | ARC57776 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates, using NF-κB2 antibody (CAB22279) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s. |
Related Products
Phospho-NF-κB2-S866 Monoclonal Antibody (CABP1367)
€139 - €609
NF-κB2 Rabbit Polyclonal Antibody (CAB5567)
€139 - €419
NF-κB2 Rabbit Polyclonal Antibody (CAB11163)
€139 - €419
