The NF-?B2 Monoclonal Antibody is a powerful tool for researchers studying the NF-?B2 protein, a key player in the regulation of immune responses. This antibody, generated in mice, exhibits high specificity and sensitivity for detecting NF-?B2 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.NF-?B2, also known as p52, is a critical component of the NF-?B signaling pathway that mediates immune and inflammatory responses. Dysregulation of NF-?B2 has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
By targeting NF-?B2, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies.The NF-?B2 Monoclonal Antibody from AssayGenie is a reliable tool for investigating the role of NF-?B2 in immune regulation and disease pathogenesis. Its high specificity and sensitivity ensure accurate and reproducible results, making it a valuable asset for studies in immunology, oncology, and inflammatory disease research.
Product Name:
NF-κB2 Monoclonal Antibody
SKU:
CAB22279
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human NF-κB2 (NP_001070962.1).
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4791
Clone Number:
ARC57776
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NF-κB2 antibody (CAB22279) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
