The NEXN Polyclonal Antibody (CAB13136) is a cutting-edge research tool designed for the study of NEXN, a critical protein involved in cellular processes such as cell adhesion and migration. This high-quality antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the NEXN protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an essential tool for investigations in cell biology and cancer research.NEXN, also known as Nexilin, plays a pivotal role in maintaining cell structure and function, making it a key target for understanding processes like cell motility and tissue development.
Its involvement in various cellular pathways highlights its importance in disease contexts such as cancer, cardiovascular disorders, and muscle diseases. Research into NEXN's function is crucial for developing targeted therapies that may impact these conditions, making the NEXN Polyclonal Antibody an invaluable asset for researchers aiming to unravel the complexities of cellular biology.
Product Name:
NEXN Rabbit Polyclonal Antibody
SKU:
CAB13136
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 516-675 of human NEXN (NP_653174.3).
Cell junction, Cytoplasm, Z line, adherens junction, cytoskeleton, myofibril, sarcomere.
Calculated MW:
81kDa
Observed MW:
81kDa
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
91624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NEXN Rabbit pAb (CAB13136) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
