ASAH2 Rabbit Polyclonal Antibody (CAB7985)
- SKU:
- CAB7985
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | ASAH2 Rabbit Polyclonal Antibody |
SKU: | CAB7985 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 531-780 of human ASAH2 (Q9NR71). |
Sequence: | SLAI TAIP GEFT TMSG RRLR EAVQ AEFA SHGM QNMT VVIS GLCN VYTH YITT YEEY QAQR YEAA STIY GPHT LSAY IQLF RNLA KAIA TDTV ANLS RGPE PPFF KQLI VPLI PSIV DRAP KGRT FGDV LQPA KPEY RVGE VAEV IFVG ANPK NSVQ NQTH QTFL TVEK YEAT STSW QIVC NDAS WETR FYWH KGLL GLSN ATVE WHIP DTAQ PGIY RIRY FGHN RKQD ILKP AVIL SFEG TSPA FEVV TI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | HNAC1; BCDase; LCDase; NCDase; N-CDase; ASAH2 |
Positive Sample: | Mouse kidney,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type II membrane protein. |
Calculated MW: | 86kDa |
Observed MW: | 100kDa |
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
Purification Method: | Affinity purification |
Gene ID: | 56624 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |