The Neurotrimin Polyclonal Antibody (CAB8994) is a valuable tool for researchers studying the protein Neurotrimin, which is known for its involvement in various biological processes, including neuronal development and cell adhesion. Raised in rabbits, this antibody offers high reactivity with human samples and has been validated for use in Western blot applications.Neurotrimin, a cell adhesion molecule belonging to the IgLON family, plays a crucial role in neural development and synaptic plasticity. By binding to Neurotrimin, this antibody enables the detection and analysis of the protein in various cell types, making it an ideal choice for studies in neuroscience and neurobiology.
The significance of Neurotrimin in neuronal function and development makes it a promising target for research into neurological disorders such as autism, Alzheimer's disease, and schizophrenia. Understanding the role of Neurotrimin in these conditions may provide valuable insights into potential therapeutic strategies.Overall, the Neurotrimin Polyclonal Antibody (CAB8994) is a reliable tool for researchers looking to investigate the function and regulation of Neurotrimin in both normal and pathological conditions, advancing our understanding of neurobiology and potential therapeutic targets for neurological disorders.
Product Name:
NTM Rabbit Polyclonal Antibody
SKU:
CAB8994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-316 of human NTM (NP_001137531.1).
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
50863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NTM antibody (CAB8994) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
