NRP2 Rabbit Polyclonal Antibody (CAB2581)
- SKU:
- CAB2581
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | NRP2 Rabbit Polyclonal Antibody |
SKU: | CAB2581 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human NRP2 (NP_957718.1). |
Sequence: | RGQP DPPC GGRL NSKD AGYI TSPG YPQD YPSH QNCE WIVY APEP NQKI VLNF NPHF EIEK HDCK YDFI EIRD GDSE SADL LGKH CGNI APPT IISS GSML YIKF TSDY ARQG AGFS LRYE IFKT GSED CSKN FTSP NGTI ESPG FPEK YPHN LDCT FTIL AKPK MEII LQFL IFDL EHDP LQVG EGDC KYDW LDIW DGI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | NP2; NPN2; PRO2714; VEGF165R2; NRP2 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 105kDa |
Observed MW: | 130kDa |
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Purification Method: | Affinity purification |
Gene ID: | 8828 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |