Neuropilin-1 (NRP1) Monoclonal Antibody (CAB22213)
- SKU:
- CAB22213
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | Neuropilin-1 (NRP1) Monoclonal Antibody |
SKU: | CAB22213 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-644 of human Neuropilin-1 (NRP1) (NP_003864.5). |
Sequence: | FRND KCGD TIKI ESPG YLTS PGYP HSYH PSEK CEWL IQAP DPYQ RIMI NFNP HFDL EDRD CKYD YVEV FDGE NENG HFRG KFCG KIAP PPVV SSGP FLFI KFVS DYET HGAG FSIR YEIF KRGP ECSQ NYTT PSGV IKSP GFPE KYPN SLEC TYIV FVPK MSEI ILEF ESFD LEPD SNPP GGMF CRYD RLEI WDGF PDVG PHIG RYCG QKTP GRIR SSSG ILSM VFYT DSAI AKEG FSAN YSVL QSSV SEDF KCME ALGM ESGE IHSD QITA SSQY STNW SAER SRLN YPEN GWTP GEDS YREW IQVD LGLL RFVT AVGT QGAI SKET KKKY YVKT YKID VSSN GEDW ITIK EGNK PVLF QGNT NPTD VVVA VFPK PLIT RFVR IKPA TWET GISM RFEV YGCK ITDY PCSG MLGM VSGL ISDS QITS SNQG DRNW MPEN IRLV TSRS GWAL PPAP HSYI NEWL QIDL GEEK IVRG IIIQ GGKH RENK VFMR KFKI GYSN NGSD WKMI MDDS KRKA KSFE GNNN YDTP ELRT FPAL STRF IRIY PERA THGG LGLR MELL GCEV EAPT AGPT TPNG NLVD ECDD DQAN CHSG TGDD FQLT GGTT VLAT EKPT VIDS TIQS EFP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1 (NRP1) |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 68kDa/71kDa/103kDa |
Observed MW: | 120-135kDa |
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Purification Method: | Affinity purification |
Gene ID: | 8829 |
Clone Number: | ARC55415 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |